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Neurol India. 2019 Nov-Dec;67(6):1536-1538. doi: 10.4103/0028-3886.273649.

Recurrent Guillain-Barré Syndrome - Case Series.

Author information

1
Neurology Clinic, Clinical Center of Serbia, School of Medicine, University of Belgrade, Dr Subotica 6, Belgrade, Serbia.
2
Neurology Clinic, Clinical Center of Vojvodina, Nikole Kočiša, Novi Sad, Serbia.
3
Neurology Clinic, Clinical Center Banja Luka, Dvanaest beba, Banja Luka, Republic of Srpska, Bosnia and Herzegovina.
4
Neurology Clinic, Clinical Center Nis, Ljube Nenadovića, Nis, Serbia.

Abstract

Recurrent Guillain-Barré syndrome (RGBS) episodes appear in up to 6% of Guillain-Barré syndrome (GBS) patients. The purpose of this study was to identify patients with previous episodes of GBS and to assess their clinical features in a large cohort of adult GBS patients. GBS patients hospitalized at tertiary centers in three Balkan countries were included in the study (n = 404). We identified 13 (3.2%) patients with recurrent GBS (RGBS). The male to female ratio was 3: 1. All RGBS patients had two episodes of the disease. The most common GBS subtype in both episodes of the disease was acute inflammatory demyelinating polyradiculoneuropathy (AIDP) (77%, first episode; 85%, second episode). Around 23% of patients presented with a different variant during the second GBS attack. Disability seems to be equally severe at both episodes (P > 0.05). Recurrent GBS was registered in 3% of our GBS patients. The majority of them were younger males. Different GBS subtypes were found to recur.

KEYWORDS:

Disability; Guillain-Barré syndrome; recurrent episode; variants

PMID:
31857555
DOI:
10.4103/0028-3886.273649
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