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Neurol India. 2019 Nov-Dec;67(6):1536-1538. doi: 10.4103/0028-3886.273649.

Recurrent Guillain-Barré Syndrome - Case Series.

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Neurology Clinic, Clinical Center of Serbia, School of Medicine, University of Belgrade, Dr Subotica 6, Belgrade, Serbia.
Neurology Clinic, Clinical Center of Vojvodina, Nikole Kočiša, Novi Sad, Serbia.
Neurology Clinic, Clinical Center Banja Luka, Dvanaest beba, Banja Luka, Republic of Srpska, Bosnia and Herzegovina.
Neurology Clinic, Clinical Center Nis, Ljube Nenadovića, Nis, Serbia.


Recurrent Guillain-Barré syndrome (RGBS) episodes appear in up to 6% of Guillain-Barré syndrome (GBS) patients. The purpose of this study was to identify patients with previous episodes of GBS and to assess their clinical features in a large cohort of adult GBS patients. GBS patients hospitalized at tertiary centers in three Balkan countries were included in the study (n = 404). We identified 13 (3.2%) patients with recurrent GBS (RGBS). The male to female ratio was 3: 1. All RGBS patients had two episodes of the disease. The most common GBS subtype in both episodes of the disease was acute inflammatory demyelinating polyradiculoneuropathy (AIDP) (77%, first episode; 85%, second episode). Around 23% of patients presented with a different variant during the second GBS attack. Disability seems to be equally severe at both episodes (P > 0.05). Recurrent GBS was registered in 3% of our GBS patients. The majority of them were younger males. Different GBS subtypes were found to recur.


Disability; Guillain-Barré syndrome; recurrent episode; variants

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