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Indian J Ophthalmol. 2020 Jan;68(1):238-240. doi: 10.4103/ijo.IJO_455_19.

Novel ultrawide field fundus fluorescein angiographic findings in a patient of Takayasu arteritis on immunosuppression.

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Department of Ophthalmology, Retina, Uvea and ROP Services, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.


A 35-year-old male, a case of Takayasu arteritis on treatment with oral prednisolone and methotrexate, revealed novel ultrawide field fluorescein angiographic features in bilateral eyes. The typical features of delayed arm-retina circulation time, lobulated areas of nonperfusion in choroid, cattle trucking of red blood cells in veins, and delayed arteriovenous transit time were nicely captured. Additionally, we noted peripheral perivascular hyperfluorescence and disc hyperfluorescence. We believe these findings could possibly be used as markers of disease activity. Lack of marked capillary nonperfusion areas and marked perivascular leakage probably signifies modulation of disease activity by the immunosuppressants.


Cattle trucking; Takayasu arteritis; computed tomography angiogram; ultrawide field fundus fluorescein angiography

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