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Indian J Ophthalmol. 2020 Jan;68(1):7-14. doi: 10.4103/ijo.IJO_1151_19.

Management of corneal perforations: An update.

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Division of Ophthalmology and Visual Sciences, Queens Medical Centre, University of Nottingham, Nottingham, UK.
Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.


Corneal perforation is a potentially devastating complication that can result from numerous conditions that precipitate corneal melting. It is associated with significant morbidity and prompt intervention is necessary to prevent further complications. Causes include microbial keratitis, ocular surface disease, and autoimmune disorders and trauma. Various management options have been described in the literature to facilitate visual rehabilitation. This rview discusses the treatment options that range from temporising measures such as corneal gluing through to corneal transplantation, with decision making guided by the location, size, and underlying aetiology of the perforation.


Corneal perforation; infective keratitis; sterile corneal melt

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