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Stem Cell Res. 2019 Dec 4;42:101679. doi: 10.1016/j.scr.2019.101679. [Epub ahead of print]

Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.

Author information

1
Host‑Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany.
2
Department of Human Genetics, Hannover Medical School, Hannover, Germany.
3
Host‑Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany; Immunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address: renate.koenig@pei.de.

Abstract

Induced pluripotent stem cells (iPSCs) are a useful tool to investigate pathomechanistic and cellular processes due to their differentiation potential into different somatic cell types in vitro. Here, we have generated iPSCs from an apparently healthy male individual using an integration-free reprogramming method. The resulting iPSCs are pluripotent and display a normal karyotype. Furthermore, we demonstrate that this iPSC line can be differentiated into all three germ layers.

KEYWORDS:

Induced Pluripotent stem cells capable of differentiation into all three germ layers; Induced pluripotent stem cells from an apparently healthy individual

PMID:
31837633
DOI:
10.1016/j.scr.2019.101679
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