68Ga-ZHER2 PET/CT Reveals HER2-Positive Metastatic Gastric Cancer With Better Image Quality Than 18F-FDG

Clin Nucl Med. 2020 Feb;45(2):e101-e102. doi: 10.1097/RLU.0000000000002859.

Abstract

A 40-year-old woman with suspected recurrent HER2-positive gastric cancer underwent both F-FDG PET/CT and Ga-ZHER2 PET/CT. Both scans revealed multiple lesions in bones and the left supraclavicular lymph node. Compared with F-FDG, Ga-ZHER2 PET/CT showed better image contrast, especially in the bone lesions.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fluorodeoxyglucose F18
  • Gallium Radioisotopes
  • Humans
  • Neoplasm Metastasis
  • Positron Emission Tomography Computed Tomography / methods*
  • Positron Emission Tomography Computed Tomography / standards
  • Radiopharmaceuticals*
  • Recombinant Fusion Proteins
  • Stomach Neoplasms / diagnostic imaging*
  • Stomach Neoplasms / pathology

Substances

  • Cys-ZHER2-342 affibody
  • Gallium Radioisotopes
  • Radiopharmaceuticals
  • Recombinant Fusion Proteins
  • Fluorodeoxyglucose F18