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Ayu. 2019 Jan-Mar;40(1):27-33. doi: 10.4103/ayu.AYU_275_18.

Efficacy of Virechana (therapeutic purgation) followed by Go-Ghrita (cow ghee) in the management of Ksheena Shukra (oligozoospermia): A clinical study.

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Department of Kayachikitsa, Chaudhary Brahm Prakash Ayurved Charak Sansthan, New Delhi, India.
Department of Kayachikitsa, IPGT and RA, Gujarat Ayurved University, Jamnagar, India.
Department of Panchakarma, IPGT and RA, Gujarat Ayurved University, Jamnagar, India.
Department of PTSR, IPGT and RA, Gujarat Ayurved University, Jamnagar, India.
Department of Shalakya Tantra, Akhandanand Ayurved College, Ahmedabad, Gujarat, India.



Fertility is affected by many different cultural, environmental and socioeconomic factors, especially in developing countries where poverty and infections are common place. Infertility is the inability of a sexually active, noncontracepting couple to achieve spontaneous pregnancy in 1 year. Shodhana (biopurificatory) procedures are indicated before the administration of Vajikarana (aphrodisiac) drugs, especially Virechana Karma (therapeutic purgation) is indicated in the cases of vitiation of Shukra (seminal parameters). Go-Ghrita (cow ghee) is a rejuvenator and aphrodisiac. Maximum preparations for the diseases of Shukra and reproductive system are prepared in Go-Ghrita and reported to be useful in the management of infertility.


The present clinical study aimed to evaluate the clinical efficacy of Go-Ghrita administered after performing Virechana Karma in the management of Ksheena Shukra (oligozoospermia).

Materials and Methods:

Eligible male participants from the age group of 21 to 40 years, with sperm count of <15 million/ml, received cow ghee for 8 weeks in the dose of 10 g, after undergoing Virechana Karma with Haritakyadi Yoga. Percentage changes in the semen parameters and associated symptoms of Ksheena Shukra in comparison to baseline were the primary outcomes measured.


Go-Ghrita administered after Virechana provided 80.92% increase in total sperm count, 41.78% increase in sperm motility, 12.58% increase in normal form of sperm, 41.69% decrease in abnormal forms, and increase in semen volume by 45.22%.


Overall assessment of the therapy showed that administration of cow ghee after performing Virechana provided statistically highly significant improvement on seminal parameters.


Go-Ghrita; Haritakyadi Yoga; Ksheena Shukra; Virechana; oligozoospermia

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