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Indian J Pharmacol. 2019 Sep-Oct;51(5):346-349. doi: 10.4103/ijp.IJP_166_19. Epub 2019 Nov 26.

Case report on premature hair graying treated with Melitane 5% and oral hair supplements.

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Department of Dermatology, Sakhiya Skin Clinic, Surat, BJ Medical College, New Civil Hospital, Ahmedabad, Gujarat, India.


With chronological aging, hair turns gray. Untimely premature hair graying (PHG) may tremendously influence on cosmesis, self-credibility, and social life of the affected individuals. Consequently, early treatment is required to improve cosmetic appearance. To the best of our knowledge, until today, only one case of PHG is reported in the literature, and it occurred due to iron deficiency and successfully treated with ferrous sulfate. Herein, we delineate a case of PHG in a 14-year-old female treated with the topical formulation of Melitane 5% and oral hair supplements which resulted in boosting improvement in hair color.


Melitane; oral hair supplements; premature hair graying

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