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Middle East J Dig Dis. 2019 Oct;11(4):230-233. doi: 10.15171/mejdd.2019.154. Epub 2019 Nov 5.

Celiac Crisis in a Young Woman: Raising Awareness of a Life-Threatening Condition.

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Zanjan University of Medical Sciences. Tehran, Iran.
Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran.
Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.


Celiac crisis is a rare, acute, and life-threatening presentation of celiac disease. Its clinical presentations consist of severe watery non-bloody diarrhea, electrolyte disturbances (i.e. hypokalemia, hyponatremia, hypomagnesemia, hypocalcemia, and metabolic acidosis), hypoproteinemia, and dehydration. Here we present a 33-year-old woman who referred with profuse diarrhea, weight loss, hemodynamic instability, hypokalemia, hypoproteinemia, ascites, pancytopenia, and iron deficiency anemia. She used herbal medicines for constipation and had severe weakness after her childbirth. The patient was diagnosed as having celiac disease through pathological and serological evaluations 10 months earlier. Diagnosis of celiac crisis after ruling out the other causes of resistant celiac was made and she was treated with steroids.


Celiac crisis; Celiac disease; Diarrhea

Conflict of interest statement

CONFLICT OF INTEREST The authors declare no conflict of interest related to this work.

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