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Obes Surg. 2019 Dec 9. doi: 10.1007/s11695-019-04318-0. [Epub ahead of print]

Vitamin D Status After Gastric Bypass or Sleeve Gastrectomy over 4 Years of Follow-up.

Author information

1
Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.
2
Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation and University Teaching Trust, Salford, UK.
3
Department of Surgery, Salford Royal NHS Foundation and University Teaching Trust, Salford, UK.
4
Manchester Metropolitan University, All Saints Building, Manchester, UK.
5
University Department of Medicine, Manchester University NHS Foundation Trust, Manchester, UK.
6
Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. akheel.syed@manchester.ac.uk.
7
Department of Diabetes, Endocrinology and Obesity Medicine, Salford Royal NHS Foundation and University Teaching Trust, Salford, UK. akheel.syed@manchester.ac.uk.

Abstract

BACKGROUND:

Bariatric surgery for severe obesity can lead to micronutrient/vitamin deficiencies.

AIMS:

To study baseline and post-surgical prevalence of vitamin D deficiency in patients undergoing bariatric surgery.

PARTICIPANTS AND SETTING:

Patients undergoing bariatric surgery in a university teaching hospital in North West England.

METHODS:

We performed an observational cohort analysis of longitudinal data on vitamin D and related parameters in patients who underwent bariatric surgery. Patients were routinely recommended daily combined calcium and vitamin D supplementation post-surgery.

RESULTS:

We studied 460 patients who had completed at least 12 months post-operatively; mean (standard deviation) age was 48.0 (10.5) years, weight 144.7 (27.3) kg and body mass index 50.0 (7.6) kg/m2; 292 (63.5%) underwent gastric bypass and 168 (36.5%) sleeve gastrectomy. Vitamin D level was 33.1 (23.9) nmol/L at baseline, rising to 57.1 (23.1) nmol/L at 12 months post-surgery. Whereas 43.2% had vitamin D deficiency and 34.7% insufficiency preoperatively, 8.9% and 26.7% had deficiency and insufficiency, respectively, at 12 months with similar trends up to 4 years of follow-up. There were no significant differences between procedures or sexes in vitamin D levels or sufficiency rates.

CONCLUSION:

Vitamin D deficiency and insufficiency were prevalent pre-surgery and reduced significantly with routine supplementation post-surgery.

KEYWORDS:

Bariatric surgery; Calcium; Hyperparathyroidism; Parathyroid hormone; Vitamin D deficiency

PMID:
31820405
DOI:
10.1007/s11695-019-04318-0

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