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J Neurol Sci. 2019 Dec 2;409:116609. doi: 10.1016/j.jns.2019.116609. [Epub ahead of print]

Consensus recommendations on the management of multiple sclerosis patients in Argentina.

Author information

1
Hospital Italiano de Buenos Aires, Centro de esclerosis múltiple de Buenos Aires, Argentina. Electronic address: cristiano.edgardo@gmail.com.
2
Hospital Italiano de Buenos Aires, Centro de esclerosis múltiple de Buenos Aires, Argentina.
3
Facultad de Medicina UBA, Hospital Ramos Mejía, Centro Universitario de Esclerosis Múltiple, Argentina; Hospital Universitario Sanatorio Güemes, Argentina.
4
Hospital San Martín, Paraná, Entre Ríos, Argentina.
5
Instituto Neurociencias Cordoba, Argentina.
6
Seccion de Neuroinmunologia y Enfermedades Desmielinizantes, Servicio de Neurologia, Hospital de Clinicas Jose de San Martin, Argentina.
7
Hospital Central de Mendoza, Argentina.
8
Servicio de Neurología, Hospital Escuela de Corrientes Facultad de Medicina, U.N.N.E., Argentina.
9
Hospital San Bernardo, Salta, Argentina.
10
Institute of Neuroscience Buenos Aires - INEBA, Argentina.
11
Department of Neuroscience - Neuroimmunology Unit, Hospital Alemán, Buenos Aires, Argentina.
12
MS Section Hospital Britanico Buenos Aires, Argentina; Policlinico Municipal Sofía T. de Santamarina, Buenos Aires, Argentina.
13
Centro de Investigaciones Diabaid, Argentina; Hospital Fernández de Buenos Aires, Argentina.
14
Hospital Enrique Tornu, Buenos Aires, Argentina; Hospital Universitario Sanatorio Güemes, Argentina.
15
Department of Neurology, Institute for Neurological Research Dr Raul Carrea, FLENI, Argentina.
16
Facultad de Medicina UBA, Hospital Ramos Mejía, Centro Universitario de Esclerosis Múltiple, Argentina.
17
Clinical Research Section, Hospital Italiano de Buenos Aires, Argentina.
18
Hospital Británico de Buenos Aires, Argentina; Hospital Municipal de Vicente López Prof. Dr. Bernardo Houssay, Argentina.
19
Servicio de Neurología, Hospital Cárlos G. Durand, CABA, Buenos Aires, Argentina.
20
RIAPEM (Red Integral Asistencial al Paciente con EM), Santiago del Estero, Argentina.
21
Fundación Sinapsis Santa Rosa La Pampa, Argentina.
22
Instituto de Neurociencias de Rosario, Argentina.
23
Abogado Diplomado en Salud Pública, Argentina.
24
MS Section Hospital Britanico Buenos Aires, Argentina.
25
Hospital de Clínicas Ntra Sra del Carmen, San Miguel de Tucumán, Argentina.
26
Clinica Reina Fabiola, Instituto Lennox, Córdoba, Argentina.
27
Práctica Privada, Buenos Aires, Argentina; Servicio de Neurología, Policlínico Bancaria, Argentina.
28
Fundación Favaloro, INECO, Buenos Aires, Argentina.
29
Sección Neuroinmunología, Hospital Ramos Mejia, Buenos Aires, Argentina.
30
Departamento de Enfermedades desmielinizantes, Sanatorio Allende, Cordoba, Argentina.

Abstract

INTRODUCTION:

During the last 20 years, multiple sclerosis (MS) disease has seen major changes with new diagnostic criteria, a better identification of disease phenotypes, individualization of disease prognosis and the appearance of new therapeutic options in relapsing remitting as well as progressive MS. As a result, the management of MS patients has become more complex and challenging. The objective of these consensus recommendations was to review how the disease should be managed in Argentina to improve long-term outcomes in MS patients.

METHODS:

A panel of 36 experts in neurology from Argentina, dedicated to the diagnosis and care of MS patients, gathered both virtually and in person during 2018 and 2019 to carry out a consensus recommendation on the management of MS patients in Argentina. To achieve consensus, the methodology of "formal consensus-RAND/UCLA method" was used.

RESULTS:

Recommendations focused on diagnosis, disease prognosis, tailored treatment, treatment failure identification and pharmacovigilance process.

CONCLUSIONS:

The recommendations of these consensus guidelines attempt to optimize the health care and management of patients with MS in Argentina.

KEYWORDS:

Argentina; Consensus guideline; Diagnosis; MS care units; Multiple sclerosis; Personalized approach; Treatment management

PMID:
31816524
DOI:
10.1016/j.jns.2019.116609

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