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Cell Metab. 2019 Dec 3;30(6):1002-1004. doi: 10.1016/j.cmet.2019.11.005.

Sorting mtDNA Species-the Role of nDNA-mtDNA Co-evolution.

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1
Miller School of Medicine, University of Miami, Miami, FL, USA. Electronic address: cmoraes@med.miami.edu.

Abstract

The segregation of heteroplasmic mtDNA species was thought to be mostly stochastic. However, recent findings, including a study by Latorre-Pellicer et al. (2019) published in this issue of Cell Metabolism, provide evidence that nuclear DNA and mitochondrial DNA interactions play an important role in the sorting process.

PMID:
31801053
DOI:
10.1016/j.cmet.2019.11.005

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