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Bioinformation. 2019 Oct 9;15(9):633-639. doi: 10.6026/97320630015633. eCollection 2019.

Differential prolactin levels among male and female patients with thyroid related complains in the Hail regions of Saudi Arabia.

Author information

1
Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Hail, Saudi Arabia.
2
Department of Clinical Laboratory Science, College of Applied Medical Sciences, Shaqra University, Saudi Arabia.
3
Hail King Khaled Hospital, Hail, Saudi Arabia.
4
College of Dentistry, University of Hail, Saudi Arabia.
5
Hail Regional Laboratory, Hail, Saudi Arabia.

Abstract

Thyroid diseases are caused by autoimmunity due to hormone imbalance both in male and female patients. Therefore, it is of acute importance to measure, analyze and compare thyroid hormone levels among populations with thyroid-related complications. Hence, we examined 202 male and female thyroid patients in the Hail regions of Saudi Arabia and estimated their hormone levels. Blood samples were collected from patients and processed for the hormonal profiling such as prolactin, luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4) and TSH3. Further, measurement of thyroid gland size in the Hail population was also completed. Results of our study showed a significant difference in the level of prolactin between male and female patients. Other hormones are namely luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4), TSH3 did not show any significant difference between male and female patients with thyroid disorder. Thus, the levels of the majority of hormones, namely luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4), and TSH3, except prolactin, did not differ significantly between male and female thyroid patients. Validation of the observation using large scale population size is warranted in future investigations.

KEYWORDS:

FSH; T3; T4; TSH; hormones; luteinizing hormone; prolactin; thyroid disorders

Conflict of interest statement

The authors declare no conflicts of interest

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