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Cell. 2019 Nov 22. pii: S0092-8674(19)31220-6. doi: 10.1016/j.cell.2019.10.043. [Epub ahead of print]

Every Breath You Take: New Insights into Plant and Animal Oxygen Sensing.

Author information

1
School of Biosciences, University of Birmingham, Edgbaston, B15 2TT, UK. Electronic address: d.gibbs@bham.ac.uk.
2
School of Biosciences, University of Nottingham, Loughborough, LE12 5RD, UK. Electronic address: michael.holdsworth@nottingham.ac.uk.

Abstract

Responses to hypoxia are regulated by oxygen-dependent degradation of kingdom-specific proteins in animals and plants. Masson et al. (2019) identified and characterized the mammalian counterpart of an oxygen-sensing pathway previously only observed in plants. Alongside other recent findings identifying novel oxygen sensors, this provides new insights into oxygen-sensing origins and mechanisms in eukaryotes.

PMID:
31785834
DOI:
10.1016/j.cell.2019.10.043

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