Format

Send to

Choose Destination
J Neurosurg Spine. 2019 Nov 29:1-4. doi: 10.3171/2019.9.SPINE19915. [Epub ahead of print]

Development of pulmonary endovascular metastases following vertebroplasty: case report.

Author information

1
Divisions of1Cardiothoracic Imaging and.
2
2Department of Medicine, University of Toronto; and.
3
3Neuroradiology, Toronto Joint Department of Medical Imaging, University Health Network.
4
4Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.

Abstract

A 69-year-old man developed pulmonary metastases following vertebroplasties for pathological fractures of vertebrae T12-L4. The fractures developed due to spinal metastases from castrate-resistant prostate cancer. A CT scan performed 1 month prior indicated no evidence of pulmonary malignancy. However, CT scans performed 2 months after the vertebroplasties demonstrated intravascular pulmonary metastases distributed similarly to embolized polymethylmethacrylate. Vertebroplasty is a well-established procedure for symptomatic management of vertebral compression fractures. However, studies have demonstrated an increase in circulating tumor cells following vertebroplasties, theoretically increasing the risk of distant metastases. In this case, the chronicity and radiological findings suggest that the pulmonary intravascular metastases may have resulted from the vertebroplasties.

KEYWORDS:

CTC = circulating tumor cell; MIP = maximum intensity projection; PMMA = polymethylmethacrylate; PSA = prostate-specific antigen; complications; metastasis; oncology; prostate cancer; vertebroplasty

PMID:
31783355
DOI:
10.3171/2019.9.SPINE19915

Supplemental Content

Full text links

Icon for Sheridan PubFactory
Loading ...
Support Center