Characterizing the BCR repertoire in immune-mediated diseases

Nitya S Ramadoss; William H Robinson

doi:10.1038/s41584-019-0339-y

Characterizing the BCR repertoire in immune-mediated diseases

Nat Rev Rheumatol. 2020 Jan;16(1):7-8. doi: 10.1038/s41584-019-0339-y.

Authors

Nitya S Ramadoss^{1

2}, William H Robinson^{3

4}

Affiliations

¹ Division of Immunology and Rheumatology, Department of Medicine, Stanford University, Stanford, CA, USA.
² Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA.
³ Division of Immunology and Rheumatology, Department of Medicine, Stanford University, Stanford, CA, USA. w.robinson@stanford.edu.
⁴ Geriatric Research, Education, and Clinical Center (GRECC), VA Palo Alto Health Care System, Palo Alto, CA, USA. w.robinson@stanford.edu.

Abstract

B cells can assume protective or pathogenic roles in immune-mediated diseases (IMDs). Analysis of the B cell receptor (BCR) repertoires in six IMDs provides insights into the diversity of B cell repertoires across diseases as well as into potential pathological mechanisms and the effects of different treatments.

Publication types

Comment

MeSH terms

B-Lymphocytes
Humans
Immune System Diseases*
Receptors, Antigen, B-Cell*

Substances

Receptors, Antigen, B-Cell

Abstract

Publication types

MeSH terms

Substances

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