Dysfunctional missense variant of OAT10/SLC22A13 decreases gout risk and serum uric acid levels

Affiliations

• ¹ Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.
• ² Graduate School of Information Science and Technology, Hokkaido University, Sapporo, Japan.
• ³ Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan.
• ⁴ Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan.
• ⁵ Laboratory for Mathematics, National Defense Medical College, Tokorozawa, Japan.
• ⁶ Department of Bioinformatics and Genomics, Graduate School of Advanced Preventive Medical Sciences, Kanazawa University, Kanazawa, Japan.
• ⁷ Ryougoku East Gate Clinic, Tokyo, Japan.
• ⁸ Midorigaoka Hospital, Takatsuki, Japan.
• ⁹ Division of Nursing, National Defense Medical College, Tokorozawa, Japan.
• ¹⁰ Department of Internal Medicine, Self-Defense Forces Central Hospital, Tokyo, Japan.
• ¹¹ Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
• ¹² Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Japan.
• ¹³ Genome Medical Science Project (Toyama), National Center for Global Health and Medicine, Tokyo, Japan.
• ¹⁴ Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
• ¹⁵ Department of Medical Biochemistry, Kurume University School of Medicine, Kurume, Japan.
• ¹⁶ Department of Pharmacy, The University of Tokyo Hospital, Tokyo, Japan hmatsuo@ndmc.ac.jp tappei-tky@umin.ac.jp.
• ¹⁷ Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan hmatsuo@ndmc.ac.jp tappei-tky@umin.ac.jp.