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PLoS One. 2019 Nov 25;14(11):e0225778. doi: 10.1371/journal.pone.0225778. eCollection 2019.

Depression increases the risk of rotator cuff tear and rotator cuff repair surgery: A nationwide population-based study.

Author information

1
Division of Sports Medicine, Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan.
2
College of Medicine, Chang Gung University, Taoyuan, Taiwan.
3
Department of Psychiatry, Chang Gung Memorial Hospital, Chiayi, Taiwan.
4
Health Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi, Taiwan.

Abstract

BACKGROUND:

Chronic inflammation is known to be associated with both rotator cuff tears (RCTs) and depression. However, no epidemiological studies with a longitudinal follow-up have been performed to prove this association. We aimed to investigate whether depressed patients had an elevated risk of RCT and subsequent repair surgery compared with those without depression.

METHODS:

This retrospective cohort study comprised of patients diagnosed with depression between 2000 and 2010 (depression cohort) and patients without depression (non-depression cohort, 1:2 age and sex matched). The risk of RCT and rotator cuff repair surgery were determined during a 13-year follow-up (2000-2013) between these two cohorts.

RESULTS:

This study included 26,868 patients with depression and 53,736 patients without depression. The incidence of RCT was 648 and 438 per 100,000 person-years in the depression and non-depression cohorts, respectively. The adjusted hazard ratio (HR) was 1.46 (95% confidence interval [CI], 1.36-1.57) for depressed patients. The incidence of rotator cuff repair surgery was 28 and 18 per 100,000 person-years in the depression and non-depression cohorts, respectively. Depressed patients also had a significantly increased risk of subsequent rotator cuff repair surgery (adjusted HR = 1.46; 95% CI, 1.04-2.06).

CONCLUSION:

The present study showed that depression was associated with an increased risk of rotator cuff tear and rotator cuff repair surgery.

Conflict of interest statement

The authors have declared that no competing interests exist.

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