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Indian J Ophthalmol. 2019 Dec;67(12):2092-2094. doi: 10.4103/ijo.IJO_493_19.

Trifocal choroidal melanoma in an eye with oculodermal melanocytosis: A case report.

Author information

1
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
2
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania; Department of Ophthalmology, Ocular Oncology Service, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

Abstract

We report a case of trifocal choroidal melanoma (three separate tumors) in a 48-year-old Caucasian female who had been followed for oculodermal melanocytosis since childhood. At presentation, no tumor was present and annual examination was advised. Seventeen years later, three choroidal melanocytic lesions were detected in the right eye. Growth of each was documented, enucleation was performed, and histopathology revealed three independent choroidal melanomas. The patient developed extensive liver and bone metastases and subsequently died. Oculodermal melanocytosis is a risk factor for the development of uveal melanoma and a potential marker for worse prognosis. Careful long-term follow-up is required.

KEYWORDS:

Choroid; melanocytosis; melanoma; multifocal; trifocal

PMID:
31755472
DOI:
10.4103/ijo.IJO_493_19
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