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Indian J Ophthalmol. 2019 Dec;67(12):2078-2080. doi: 10.4103/ijo.IJO_812_19.

Intraocular amyloidosis with multifocal iris and anterior chamber translucent spherules.

Author information

1
Department of Oculoplasty and Ocular Oncology Services, Dr Shroff's Charity Eye Hospital, New Delhi, India.
2
Glaucoma Services, Dr Shroff's Charity Eye Hospital, New Delhi, India.
3
Cornea and Anterior Segment, Dr Shroff's Charity Eye Hospital, New Delhi, India.
4
National Reporting Centre for Ophthalmic Pathology, Centre for Sight, Hyderabad, Telangana, India.
5
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, 840 Walnut Street, Philadelphia, PA, USA.

Abstract

Ocular amylodosis, although a rare entity, is known to affect the conjunctiva, extraocular muscles, orbit, lacrimal gland, and skin around the eyes. Intraocular deposition of amyloid mainly confines to the vitreous and cornea. In this report, we describe two cases of intraocular amyloidosis presenting as multiple iris and anterior chamber cysts. Histopathological examination with special stain like Congo Red and Transmission Electron Microscopy confirmed the diagnosis of amyloidosis. Systemic investigations ruled out systemic association confirming the diagnosis of primary ocular amyloidosis.

KEYWORDS:

Amyloid; anterior chamber; eye; iris

PMID:
31755466
DOI:
10.4103/ijo.IJO_812_19
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