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Indian J Dent Res. 2019 Jul-Aug;30(4):590-594. doi: 10.4103/ijdr.IJDR_326_16.

In Vitro evaluation of remineralization potential of novamin on artificially induced carious lesions in primary teeth using scanning electron microscope and vickers hardness.

Author information

Department of Pedodontics and Preventive Dentistry, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.



The objective of this in vitro study was to find out the efficacy of Novamin in remineralizing enamel surface on which artificial caries lesion had been created. The changes were analyzed using Vickers Hardness Testing Machine and Scanning electron microscope (SEM).

Settings and Design:

A total of 40 primary teeth were selected and divided into two groups: Control group and SHY NM (Novamin). All the samples were subjected to ph cycle protocol and assessed using Vickers Hardness Testing Machine and Scanning electron microscope. Each demineralized sample was randomly divided into two groups: Gp I -Control group, Gp II - Novamin (SHY NM). After 10-day period of ph cycle, the obtained data was analyzed statistically.

Statistical Analysis Used:

Pre and post groups were compared by paired t test. The significance of mean difference between the groups was done by Tukey's post hoc test after ascertaining normality by Shapiro-Wilk (W) test and homogeneity of variance by Levene's test. A two-tailed P value less than 0.05 (P < 0.05) was considered statistically significant. All analyses were performed on SPSS software (Windows version 17.0).


Statistical analysis showed that bioactive glass (novamin) remineralizes artificially induced carious lesion in primary teeth.


SHY NM (Novamin) exhibited superior remineralization potential.


Bioactive glass; SHY NM (Novamin); enamel; remineralization; scanning electron microscope; vickers hardness testing machine

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