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Indian J Dent Res. 2019 Jul-Aug;30(4):487-495. doi: 10.4103/ijdr.IJDR_466_16.

Randomized clinical trial of four adhesion strategies: A 42 month study.

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Department of Operative Dentistry, Postgraduate Program in Dentistry, Paulista University, São Paulo, SP, Brazil.



The adhesives clinical effectiveness has been extensively reported for noncarious cervical lesions (NCCLs). However, there is a lack of information about the adhesive systems strategies and their effect on NCCL restoration longevity.


This study aims to evaluate a 42-month performance of four dentin adhesive systems used for the restorative treatment of NCCLs.

Settings and Design:

NCCLs were randomly divided into four groups: (1) Scotchbond multi-purpose (MP); 2: Single bond plus (SB); 3: Scotchbond SE (SE); and 4: Easy bond (EB).

Subjects and Methods:

NCCLs (125) were randomly distributed: (1) MP; (2) SB; (3) SE; and (4) EB and were restored with a nanofilled resin-composite, evaluated along 18-36-42 months.

Statistical Analysis Used:

Kruskal-Wallis test: Comparison among the adhesive systems in each period. Friedman analysis: Comparison along the periods. Kaplan-Meier: Survival analysis.


Baseline and 42-month retention (RET) rates (%) were 100/100 for MP; 100/94.74 for SB; 100/87.5 for SE; and 100/100 for EB. The cumulative failure percentage was 9.52% for MP, 9.52% SB, 15.8% SE, and 10% EB. Restorations survival was not dependent on the used adhesive type. Marginal adaptation (MA) was similar to each group, but EB presented noticeable marginal deterioration. Wear was noticed in the 3-step etch-and-rinse (MP) restorations evaluated after 42 months. For the EB, baseline and 18-month wear evaluation were statistically similar. After 36 and 42 months, wear was also similar for EB.


Adhesive systems showed similar performance within most important adhesive bonding efficiency achievement parameters: RET, MA, interfacial staining, recurrent caries, and postoperative sensitivity evaluated during 42 months.


Clinical trial; dentin adhesive; marginal adaptation; wear

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