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BMC Health Serv Res. 2019 Nov 14;19(1):834. doi: 10.1186/s12913-019-4613-0.

Economic evaluation studies in the field of HIV/AIDS: bibliometric analysis on research development and scopes (GAPRESEARCH).

Author information

1
Department of Health Economics, Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam. bach.jhu@gmail.com.
2
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA. bach.jhu@gmail.com.
3
Center of Excellence in Behavioral Medicine, Nguyen Tat Thanh University, Ho Chi Minh City, 70000, Vietnam.
4
Oxford University Clinical Research Unit, Ho Chi Minh City, 70000, Vietnam.
5
Centre for Applied Health Economics, Griffith University, Brisbane, Australia.
6
Center of Excellence in Evidence-based Medicine, Nguyen Tat Thanh University, Ho Chi Minh City, 70000, Vietnam.
7
Institute for Global Health Innovations, Duy Tan University, Da Nang, Vietnam.
8
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
9
Department of Psychological Medicine, National University Hospital, Singapore, Singapore.
10
Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.
11
Biomedical Global Institute of Healthcare Research & Technology (BIGHEART), National University of Singapore, Singapore, 117599, Singapore.

Abstract

BACKGROUND:

The rapid decrease in international funding for HIV/AIDS has been challenging for many nations to effectively mobilize and allocate their limited resources for HIV/AIDS programs. Economic evaluations can help inform decisions and strategic planning. This study aims to examine the trends and patterns in economic evaluation studies in the field of HIV/AIDS and determine their research landscapes.

METHODS:

Using the Web of Science databases, we synthesized the number of papers and citations on HIV/AIDS and economic evaluation from 1990 to 2017. Collaborations between authors and countries, networks of keywords and research topics were visualized using frequency of co-occurrence and Jaccards' similarity index. A Latent Dirichlet Allocation (LDA) analysis to categorize papers into different topics/themes.

RESULTS:

A total of 372 economic evaluation papers were selected, including 351 cost-effectiveness analyses (CEA), 11 cost-utility analyses (CUA), 12 cost-benefit analyses (CBA). The growth of publications, their citations and usages have increased remarkably over the years. Major research topics in economic evaluation studies consisted of antiretroviral therapy (ART) initiation and treatment; drug use prevention interventions and prevention of mother-to-child transmission interventions. Moreover, lack of contextualized evidence was found in specific settings with high burden HIV epidemics, as well as emerging most-at-risk populations such as trans-genders or migrants.

CONCLUSION:

This study highlights the knowledge and geographical discrepancies in HIV/AIDS economic evaluation literature. Future research directions are also informed for advancing economic evaluation in HIV/AIDS research.

KEYWORDS:

Bibliometric; Content analysis; Economic evaluation; HIV/AIDS; Health economics

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