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The Bioelectric Circuitry of the Cell.

Authors

Tuszynski JA4,5,6.

Editors

In: Makarov S1, Horner M2, Noetscher G3, editors.

Source

Brain and Human Body Modeling: Computational Human Modeling at EMBC 2018 [Internet]. Cham (CH): Springer; 2019. Chapter 11.
2019 Aug 28.

Author information

1
Massachusetts General Hospital, Boston, MA, USA
2
ANSYS, Inc., Evanston, IL, USA
3
Worcester Polytechnic Institute, Worcester, MA, USA
4
Department of Oncology, University of Alberta, Edmonton, AB, Canada
5
Department of Physics, University of Alberta, Edmonton, AB, Canada
6
DIMEAS, Politecnico di Torino, Turin, Italy

Excerpt

This chapter presents an overview of electric conduction in living cells when viewed as a composition of bioelectric circuits. We review the cell’s components that are known to exhibit electric conduction properties and represent them as parts of a complex circuitry. In particular, we discuss conductivity of the membrane, ion channels, actin filaments, DNA, and microtubules, each of which play important roles in the biological functioning of the cell. A new picture emerges where electrical conduction within the cell is taking place in an integrated fashion and may explain synchronization and orchestration of the cell dynamics.

Copyright 2019, The Author(s).

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