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J Med Vet Mycol. 1988 Jun;26(3):163-71.

Auxotrophic heterozygosities and the ploidy of Candida parapsilosis and Candida krusei.

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Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892.


Evidence is presented that the type strain of Candida parapsilosis, ATCC 22019, is heterozygous MET/met and that Candida krusei Y 10930 is heterozygous URA/ura. This URA gene determines orotidine-5'-phosphate decarboxylase activity. Because each of these strains is demonstrably disomic for at least one chromosome, they are not haploid but must be diploid or aneuploid.

[Indexed for MEDLINE]

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