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Clin Neurol Neurosurg. 2020 Jan;188:105586. doi: 10.1016/j.clineuro.2019.105586. Epub 2019 Nov 4.

Paroxismal non-kinesigenic dyskinesia and hemidystonia associated with silent celiac disease.

Author information

1
Department of Neurology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, Croatia. Electronic address: petrabago@yahoo.com.
2
Department of Neurosurgery, University Clinical Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia.
3
Department of Neurology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, Croatia.

Abstract

Paroxismal non-kinesigenic dyskinesia (PNKD) is a rare movement disorder manifesting as choreatic/dystonic movements, usually lasting from minutes to up to 4 h, with perserved consciousness during attacks. Primary PNKD are idiopathic or genetic disorders while secondary PNKD are associated with various neurologic and medical conditions. We present a case with PNKD and right sided hemidystonia in association with celiac disease, responsive to gluten-free diet, not previously reported in available literature. In conclusion, diagnostic tests for celiac disease should be a part of etiological investigations in patients with otherwise unexplained movement disorders including PKND. Gluten free diet could produce a favorable clinical response in those patients.

KEYWORDS:

Celiac disease; Clinical presentation; PNKD (paroxysmal non-kinesigenic dyskinesia)

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