Format

Send to

Choose Destination
Catheter Cardiovasc Interv. 2019 Nov 6. doi: 10.1002/ccd.28565. [Epub ahead of print]

Efficacy of plaque debulking for bifurcated or ostial lesions by directional coronary atherectomy prior to second-generation drug eluting stenting.

Author information

1
Department of Cardiovascular Medicine, Toyohashi Heart Center, Aichi, Japan.
2
Department of Cardiovascular Medicine, Nagoya Heart Center, Aichi, Japan.
3
Department of Cardiovascular Medicine, Gifu Heart Center, Gifu, Japan.

Abstract

OBJECTIVES:

We sought to evaluate the efficacy of plaque debulking by directional coronary atherectomy (DCA) prior to second-generation drug-eluting stent (DES) implantation for bifurcated coronary lesions.

BACKGROUND:

Percutaneous coronary intervention (PCI) for bifurcated lesions still remains complex and challenging in terms of restenosis or stent thrombosis regardless of whether simple or complex stenting is used.

METHODS:

Patients with bifurcated lesions were enrolled in this prospective multicenter registry. Pre-second-generation DES plaque debulking with a novel DCA catheter (ATHEROCUT®, Nipro Co., Osaka, Japan) was conducted. All patients were scheduled to perform a follow up angiography (9-12 month coronary angiography or coronary computed tomography). The primary end point was target vessel failure (TVF) at follow up. Secondary end points were procedure-related events and major adverse cardiac events at 1 year.

RESULTS:

A total of 77 patients with bifurcated lesions were enrolled. PCI with DCA was performed successfully in all cases without any major procedure-related event and only one case required complex stenting. The TVF rate at 9-12 month follow up was 3.9% (3 of 77) and those were all associated with revascularization of the target vessel. Restenosis was only observed at the ostium of the main-branch in three cases. No death, coronary artery bypass grafting, or myocardial infarction were reported for any patients within the first year.

CONCLUSION:

DCA before second-generation DES implantation can possibly avoid complex stenting and provide a good mid-term outcome in patients with bifurcated lesions.

KEYWORDS:

bifurcated lesion; directional coronary atherectomy; drug eluting stent

PMID:
31691499
DOI:
10.1002/ccd.28565

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center