[Lymphopenia and variations in T and B lymphocytes appearing immediately after irradiation (author's transl)]

J Radiol. 1979 Nov;60(11):695-700.
[Article in French]

Abstract

Immunity tests were conducted in 21 patients with cancer, before and two months after irradiation. T and B lymphocyte counts were normal before irradiation when compared to a control group. Lymphopenia was present after irradiation affecting mainly the T lymphocytes (P = 0.005), whereas changes in B lymphocytes were not significant. These results suggest that irradiation has an immunosuppressive effect which should be studied in greater detail to establish possible therapeutic applications.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • B-Lymphocytes / cytology
  • B-Lymphocytes / radiation effects*
  • Female
  • Humans
  • Leukocyte Count
  • Lymphopenia / etiology*
  • Male
  • Middle Aged
  • Neoplasms / radiotherapy
  • Radiotherapy / adverse effects*
  • Rosette Formation
  • T-Lymphocytes / cytology
  • T-Lymphocytes / radiation effects*