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Indian J Palliat Care. 2019 Oct-Dec;25(4):580-586. doi: 10.4103/IJPC.IJPC_90_19.

Principles of Management of Extremity Skeletal Metastasis.

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Department of Bone and Soft Tissue, Tata Memorial Hospital, Mumbai, Maharashtra, India.
Department of Orthopaedics, DY Patil School of Medicine, Navi Mumbai, Maharashtra, India.
Division of Orthopaedic Surgery, Glasgow Royal Infirmary, Glasgow, Scotland, UK.


Understanding the epidemiology of extremity skeletal metastasis and the factors deciding the treatment decision-making are essential in developing a diagnostic and treatment strategy. This leads to optimum care and reduces disease-related burden. With the evolution of medical, radiation therapy, and surgical methods, cancer care has improved the quality of life for patients with improved survival and functional status in patients with skeletal metastasis. Based on the currently available literature, we have described a step-wise evaluation and management strategy of metastatic extremity bone disease. The present review article addresses various aspects and related controversies related to evaluation, staging, and treatment options in the management of extremity bone metastasis. This article also highlights the role of multidisciplinary involvement in management of extremity skeletal metastasis.


Angioembolization; endoprosthesis; megaprosthesis; pathological fracture; radiotherapy; skeletal metastasis

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