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MMWR Morb Mortal Wkly Rep. 2019 Nov 1;68(43):985-989. doi: 10.15585/mmwr.mm6843e1.

Update: Characteristics of Patients in a National Outbreak of E-cigarette, or Vaping, Product Use-Associated Lung Injuries - United States, October 2019.

Author information

1
National Center for Immunization and Respiratory Diseases, CDC.
2
Center for Surveillance, Epidemiology, and Laboratory Services, CDC.
3
National Center for Emerging and Zoonotic Infectious Diseases, CDC.
4
California Department of Public Health.
5
Epidemic Intelligence Service, Center for Global Health, CDC.
6
Agency for Toxic Substances and Disease Registry, CDC.
7
Epidemic Intelligence Service, National Center for Injury Prevention and Control, CDC.
8
National Center for Environmental Health, CDC.
9
National Center for Chronic Disease Prevention and Health Promotion, CDC.
10
Northrop Grumman.
11
Epidemic Intelligence Service, National Center for Environmental, CDC.
12
Epidemic Intelligence Service, National Center for Immunization and Respiratory Diseases, CDC.
13
Epidemic Intelligence Service, National Center for Chronic Disease Prevention and Health Promotion, CDC.
14
Council of State and Territorial Epidemiologists.
15
, National Center for Environmental Health, CDC.
16
G2S Corporation.
17
Utah Department of Health.
18
National Center for Injury Prevention and Control, CDC.
19
Epidemic Intelligence Service, National Center on Birth Defects and Developmental Disabilities CDC.
20
North Carolina Department of Health and Human Services.
21
Illinois Department of Health.
22
National Center on Birth Defects and Developmental Disabilities, CDC.
23
Mercer University.
24
Office of the Director, CDC.
25
New Mexico Department of Health.
26
Illinois Department of Public Health.
27
Minnesota Department of Health.
28
Epidemic Intelligence Service, Center for Surveillance, Epidemiology, and Laboratory Services, CDC.
29
Wisconsin Department of Health.
30
, Center for Surveillance, Epidemiology, and Laboratory Services, CDC.
31
Office of the Deputy Director for Non-Infectious Diseases, Office of the Director, CDC.
32
Epidemic Intelligence Service, National Center for Emerging and Zoonotic Infectious Diseases, CDC.
33
Wisconsin Department of Health Services.
34
Eagle Medical Services.
35
Epidemic Intelligence Service, National Institute for Occupational Safety and Health.

Erratum in

Abstract

CDC, the Food and Drug Administration, state and local health departments, and other public health and clinical stakeholders are investigating a national outbreak of electronic-cigarette (e-cigarette), or vaping, product use-associated lung injury (EVALI) (1). As of October 22, 2019, 49 states, the District of Columbia (DC), and the U.S. Virgin Islands have reported 1,604 cases of EVALI to CDC, including 34 (2.1%) EVALI-associated deaths in 24 states. Based on data collected as of October 15, 2019, this report updates data on patient characteristics and substances used in e-cigarette, or vaping, products (2) and describes characteristics of EVALI-associated deaths. The median age of EVALI patients who survived was 23 years, and the median age of EVALI patients who died was 45 years. Among 867 (54%) EVALI patients with available data on use of specific e-cigarette, or vaping, products in the 3 months preceding symptom onset, 86% reported any use of tetrahydrocannabinol (THC)-containing products, 64% reported any use of nicotine-containing products, and 52% reported use of both. Exclusive use of THC-containing products was reported by 34% of patients and exclusive use of nicotine-containing products by 11%, and for 2% of patients, no use of either THC- or nicotine-containing products was reported. Among 19 EVALI patients who died and for whom substance use data were available, 84% reported any use of THC-containing products, including 63% who reported exclusive use of THC-containing products; 37% reported any use of nicotine-containing products, including 16% who reported exclusive use of nicotine-containing products. To date, no single compound or ingredient used in e-cigarette, or vaping, products has emerged as the cause of EVALI, and there might be more than one cause. Because most patients reported using THC-containing products before symptom onset, CDC recommends that persons should not use e-cigarette, or vaping, products that contain THC. In addition, because the specific compound or ingredient causing lung injury is not yet known, and while the investigation continues, persons should consider refraining from the use of all e-cigarette, or vaping, products.

PMID:
31671085
PMCID:
PMC6822806
DOI:
10.15585/mmwr.mm6843e1
[Indexed for MEDLINE]
Free PMC Article

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