Format

Send to

Choose Destination
Hematol Oncol Clin North Am. 2019 Dec;33(6):1027-1039. doi: 10.1016/j.hoc.2019.08.010. Epub 2019 Oct 1.

Treatment Toxicity: Radiation.

Author information

1
Department of Radiation Oncology, University of Massachusetts Medical School/UMass Memorial Health Care, 55 Lake Avenue North, Worcester, MA 01655, USA; Imaging and Radiation Oncology Core (IROC), 640 George Washington Highway, Building B, Suite 201, Lincoln, RI 02865, USA. Electronic address: TJ.Fitzgerald@umassmemorial.org.
2
Department of Radiation Oncology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
3
University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
4
Department of Radiation Oncology, University of Massachusetts Medical School/UMass Memorial Health Care, 55 Lake Avenue North, Worcester, MA 01655, USA.

Abstract

Intentional and unintentional radiation exposures have a powerful impact on normal tissue function and can induce short-term and long-term injury to all cell systems. Radiation effects can lead to lifetime-defining health issues for a patient and can produce complications to all organ systems. Providers need to understand acute and late effects of radiation treatment and how the fingerprints of therapy can have an impact on health care in later life. This article reviews current knowledge concerning normal tissue tolerance with therapy.

KEYWORDS:

Cell damage; Normal tissue tolerance; Radiation exposure dose volume; Treatment effects

PMID:
31668204
DOI:
10.1016/j.hoc.2019.08.010

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center