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Crohns Colitis 360. 2019 Oct;1(3):otz033. doi: 10.1093/crocol/otz033. Epub 2019 Oct 15.

Reclassifying Pseudopolyps in Inflammatory Bowel Disease: Histologic and Endoscopic Description in the New Era of Mucosal Healing.

Author information

1
Department of Gastroenterology and Hepatology, University of California Los Angeles, Los Angeles, California.
2
Department of Gastroenterology and Hepatology, University of Miami, Miami, Florida.
3
Department of Medicine, University of Miami, Miami, Florida.
4
Nebraska Food for Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska.
5
Ameripath, Shreveport, Louisiana.

Abstract

Introduction:

In this study, we identify the frequency of pseudopolyps (PPs) with normal histology and their association to surrounding tissue.

Methods:

Patients were enrolled in a study identifying endoscopic characteristics of PPs (n = 29) or were collected as part of our IBD biobank (n = 16). Statistical analysis included Stata v.15.0. chi-square and Student t-test.

Results:

A total of 45 patients with 117 PP biopsies were identified. More patients with healed PP were in endoscopic remission compared with those with inflammatory PP (82.6% vs 17.4%, respectively).

Conclusion:

This is the first study to find mucosal healing of PPs and its association with deep remission.

KEYWORDS:

healed pseudopolyps; inflammatory bowel disease; inflammatory pseudopolyps

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