Send to

Choose Destination
MBio. 2019 Oct 29;10(5). pii: e02461-19. doi: 10.1128/mBio.02461-19.

A Bumpy Pathway to Stationary-Phase Survival in Bacillus subtilis.

Author information

Department of Microbiology and Cell Science, University of Florida, Space Life Sciences Laboratory, Merritt Island, Florida, USA


Bacillus subtilis cells can mount a number of responses to nutritional deprivation but ultimately either form dormant spores or enter a metabolically quiescent state. In a recent article (mBio 10:e01414-19,, 2019), R. Hashuel and S. Ben-Yehuda report on a novel means by which nutrient-starved B. subtilis cells escape from aging (days-old) colonies by accumulating mutations enabling them to continue growth under nutrient-limited conditions. They postulate that such a strategy may be a major factor determining the dynamics of bacterial populations in natural environments.


Bacillus subtilis ; mutation; nutrient depletion; stationary phase

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center