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Phys Med Biol. 2019 Oct 25. doi: 10.1088/1361-6560/ab5130. [Epub ahead of print]

Characterization of an x-ray source with a partitioned diamond-tungsten target for electronic brachytherapy with 3D beam directionality.

Author information

1
Triple Ring Technologies, Newark, California, UNITED STATES.
2
Sensus Healthcare, Boca Raton, UNITED STATES.
3
Triple Ring Technologies , 39655 EUREKA DR., Newark, 94560, UNITED STATES.

Abstract

The SculpturaTMis a new high-dose-rate electronic brachytherapy system developed by Sensus Healthcare. By combining a steerable electron beam with a partitioned diamond-tungsten x-ray target, the x-ray source of the SculpturaTMis capable of producing highly anisotropic dose distributions, thus achieving true 3D beam directionality. This article reports the spectral and dosimetric characterization of the SculpturaTMx-ray source through a combination of measurements and Monte Carlo simulations for operating points between 50 - 100 kV. Excellent agreement (~5% discrepancy) between the simulations and measurements was obtained for in-air dose rate characterization. The validated simulations were then used to calculate the dose distribution in water. Dose rates of >2 cGy/min/µA can be produced at 100 kV, thus delivering 10 Gy in 1 minute for typical operating conditions. The dose distributions are sharply peaked, with a full-width at half-maximum azimuth of about 100°.

KEYWORDS:

3D beam directionality; Monte Carlo simulations; beam sculpting; dosimetry; electronic brachytherapy; high dose rate; intraoperative radiation therapy

PMID:
31652422
DOI:
10.1088/1361-6560/ab5130

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