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Nucleic Acids Res. 2019 Oct 23. pii: gkz920. doi: 10.1093/nar/gkz920. [Epub ahead of print]

WormBase: a modern Model Organism Information Resource.

Author information

1
Informatics and Bio-computing Platform, Ontario Institute for Cancer Research, Toronto, ON M5G0A3, Canada.
2
Division of Biology and Biological Engineering 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
3
European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
4
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
5
Department of Genetics, Washington University School of Medicine, St Louis, MO 63110, USA.

Abstract

WormBase (https://wormbase.org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model system for studies across a broad range of basic biological processes. Toward this mission, WormBase efforts are arranged in three primary facets: curation, user interface and architecture. In this update, we describe progress in each of these three areas. In particular, we discuss the status of literature curation and recently added data, detail new features of the web interface and options for users wishing to conduct data mining workflows, and discuss our efforts to build a robust and scalable architecture by leveraging commercial cloud offerings. We conclude with a description of WormBase's role as a founding member of the nascent Alliance of Genome Resources.

PMID:
31642470
DOI:
10.1093/nar/gkz920

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