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Dev Cell. 2019 Oct 21;51(2):133-134. doi: 10.1016/j.devcel.2019.09.020.

Conducting Chromatin Motion: Actin Dynamizes Contents of the Oocyte Nucleus.

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School of Biochemistry, University of Bristol, BS8 1TD Bristol, UK. Electronic address:


Architecture of the nucleus is intimately linked to fundamental cellular processes carried out within it, such as maintenance of genome stability and gene expression. In this issue of Developmental Cell, Almonacid et al. (2019) show that actin-dependent shape fluctuations of the oocyte nucleus promote the movement of chromatin inside the nucleoplasm.

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