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Somat Cell Mol Genet. 1988 Mar;14(2):217-21.

Structural gene encoding human factor XII is located at 5q33-qter.

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  • 1Department of Human Genetics, University of Manitoba, Canada.


The gene encoding human factor XII (F12) or Hageman factor has been mapped to 5q33-qter. This has been achieved by analyzing the results obtained from hybridizing a cloned fragment from the factor XII gene to a panel of human-hamster somatic cell hybrid DNAs and also by in situ hybridization to normal human metaphase cells. The previously reported results localizing F12 to 6p23 are discussed.

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