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Middle East Afr J Ophthalmol. 2019 Sep 30;26(3):178-180. doi: 10.4103/meajo.MEAJO_303_17. eCollection 2019 Jul-Sep.

Multicolor Imaging Characteristics of Best's Vitelliform Macular Dystrophy.

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Retina Services, Kamalnayan Bajaj Sankara Nethralaya, Kolkata, West Bengal, India.
Retina Services, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.
Sri Bhagwan Mahavir Vitreoretina Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.


A 40-year-old woman presented with vitellieruptive stage of Best's vitelliform macular dystrophy (BVMD) in the right eye and pseudohypopyon stage in the left eye. She underwent comprehensive ophthalmic examination and fundus imaging using multicolor (MC) imaging technology of Spectralis (Heidelberg Engineering, Heidelberg, Germany) spectral-domain-optical coherence tomography system. Composite MC imaging revealed larger area of retinal pigment epithelium atrophy in vitellierruptive stage of the disease in the right eye compared to color fundus photograph. Retinal elevation in the pseudohypopyon stage was better delineated on composite MC and blue reflectance images in the left eye. Subretinal lipofuscin was best seen in green reflectance and short-wave autofluorescence images. The present case reports the MC imaging features of BVMD.


Best's disease; Best's vitelliform macular dystrophy; lipofuscin; multicolor imaging; reflectance image

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