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Middle East Afr J Ophthalmol. 2019 Sep 30;26(3):123-126. doi: 10.4103/meajo.MEAJO_62_18. eCollection 2019 Jul-Sep.

Has Spectral-Domain Optical Coherence Tomography Retinal Nerve Fiber Layer Assessment Become the Method of Choice for Glaucoma Evaluation in Clinical Practice?

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Department of Ophthalmology, Alluri Sitaramaraju Academy of Medical Sciences, Eluru, Andhra Pradesh, India.
Department of Ophthalmology, Father Muller's Medical College, Mangalore, Karnataka, India.
Department of Ophthalmology, Kasturba Medical College, Manipal, Karnataka, India.



The aim of the study was to assess the role of spectral-domain optical coherence tomography (SD-OCT) as a method of choice for early glaucoma diagnosis in glaucoma suspects.


This was a retrospective cross-sectional study.


After a comprehensive ophthalmic examination and visual field analysis, 20 patients were included in each of the three groups: Normal group, possible glaucoma, definitive glaucoma, respectively. The optic nerve head (ONH) and peripapillary retinal nerve fiber layer parameters of participants were analyzed using SD-OCT optic disc cube protocol scans. Data was analyzed using one.way analysis of variance test.


ONH RNFL defects in possible glaucoma patients were frequently found in superior, inferior, and temporal quadrants.


Diagnostic capability of SD-OCT parameters for detection of structural changes in the ONH and retinal nerve fiber layer differed in three groups significantly. Hence, using SD-OCT has become an imperative and quick way of timely diagnosis of glaucoma in private practice.


Glaucoma; retinal nerve fiber layer defects; spectral-domain optical coherence tomography

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