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Indian J Pathol Microbiol. 2019 Oct-Dec;62(4):582-585. doi: 10.4103/IJPM.IJPM_272_19.

Metastatic hepatocellular carcinoma to the parotid gland: A diagnostic dilemma with review of the literature.

Author information

1
Department of Pathology, Dharamshila Narayana Hospital, New Delhi, India.
2
Department of Oral and Maxillofacial Pathology, Dharamshila Narayana Hospital, New Delhi, India.

Abstract

Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy and is a leading cause of cancer-related death worldwide. It has a very aggressive clinical course, with a mean survival rate of much less than a year if left untreated. Here, we present a case of a 68-year-old male with progressively enlarging painful right facial swelling, involving the ramus and condyle of mandible on contrast-enhanced computed tomography mimicking an osteosarcoma. Eventually, the final diagnosis of HCC metastatic to the right parotid gland was made. We report a case of a rare metastasis of HCC to the parotid gland. Furthermore, the present case demonstrates the importance of tissue biopsy and immunohistochemistry for obtaining an accurate final diagnosis.

KEYWORDS:

HepPar-1; Hepatocellular carcinoma; IHC; parotid

PMID:
31611444
DOI:
10.4103/IJPM.IJPM_272_19

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