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Pediatr Allergy Immunol. 2019 Oct 8. doi: 10.1111/pai.13135. [Epub ahead of print]

Allergic sensitisation in infants younger than one year of age.

Author information

1
Oslo University Hospital, Department of Paediatrics, Oslo, Norway.
2
University of Oslo, Faculty of Medicine, Institute of Clinical Medicine, Oslo, Norway.
3
Østfold Hospital Trust, Norway.
4
Innlandet Hospital Trust, Elverum, Norway.
5
VID Specialized University, Oslo, Norway.
6
Oslo University Hospital, Department of Dermatology, Oslo, Norway.
7
Furst Medical Laboratory.

Abstract

Allergic sensitisation, usually reported by specific immunoglobulin E (s-IgE) or skin prick test, is a significant predictor of asthma, allergic rhinitis and food allergy. Also, polysensitisation as well as higher levels of s-IgE to any one particular allergen appears to be associated with severe and/or complex (comorbid) allergic disease. However, information on early infant allergy sensitisation is largely lacking, and with conflicting results. In the Danish DARC birth cohort 12.5% of 3-month old infants were sensitised, while 16.7% of the 404 infants were sensitised at six months.

KEYWORDS:

allergic disease; allergic sensitisation; asthma; atopic dermatitis; bronchiolitis; child

PMID:
31594030
DOI:
10.1111/pai.13135

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