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Ginekol Pol. 2019;90(9):507-512. doi: 10.5603/GP.2019.0088.

A comparison in an experimental rat model of the effects on adhesion formation of different hemostatic methods used in abdominopelvic surgery.

Author information

1
Department of Obstetrics and Gynecology, Birecik State Hospital, Şanlıurfa, Turkey.
2
Department of Obstetrics and Gynecology, Kahramanmaraş Sütçü İmam University, School of Medicine, Turkey. muratbakacak46@gmail.com.
3
Department of General Surgery, Kahramanmaraş Sütçü İmam University, School of Medicine, Turkey.
4
Private Clinic, Kahramanmaraş, Turkey.
5
Department of Histology and Embriyology, Kahramanmaraş Sütçü İmam University, School of Medicine, Turkey.
6
Department of Anesthesiology and Reanimation, Kahramanmaraş Sütçü İmam University, School of Medicine, Turkey.
7
Department of Pathology, Kahramanmaraş Sütçü İmam University, School of Medicine, Turkey.

Abstract

OBJECTIVES:

To evaluate the effects of different hemostasis methods used in abdominal surgery on the development ofabdominal adhesion.

MATERIAL AND METHODS:

A total of 48 Wistar albino female rats were separated into six groups; Group 1 - Control group,Group 2 - Hemorrhage group, Group 3 - Electrocoautery group, Group 4 - Gel Spon-P®, Group 5 - PAHACEL®, andGroup 6 - Ankaferd-Blood Stopper®. Adhesions that developed were scored according to the Knightly classification andthe prevalence of adhesions according to the Linsky classification. The total adhesion score was calculated as the total ofthe severity and prevalence scores.

RESULTS:

The lowest total adhesion values were determined in Group 1 (control) and the highest adhesion values were inGroup 2 (hemorrhage) group in terms of all parameters. The adhesion values in Group 3, where the rats were administeredhemostasis with electrocautery were similar to those of Group 2 (hemorrhage). When the alternative methods were evaluated,the lowest adhesion scores were in Group 6 (Ankaferd-Blood Stopper®).

CONCLUSIONS:

In cases of minor pelvic or abdominal bleeding, not providing hemostasis or applying hemostasis withelectrocautery can increase the development of intra-abdominal adhesions. The use of alternative hemostatic materialsinstead of electrocautery for hemostasis may reduce the formation of adhesions.

KEYWORDS:

abdominal adhesion; hemostasis; hemostatic agents; intra-abdominal hemorrhage; pelvic surgery

PMID:
31588547
DOI:
10.5603/GP.2019.0088
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