Don't Trust Your Gut: When Gut Microbiota Disrupt Fertility

Mauro S B Silva; Paolo Giacobini

doi:10.1016/j.cmet.2019.09.005

Don't Trust Your Gut: When Gut Microbiota Disrupt Fertility

Cell Metab. 2019 Oct 1;30(4):616-618. doi: 10.1016/j.cmet.2019.09.005.

Authors

Mauro S B Silva¹, Paolo Giacobini²

Affiliations

¹ University of Lille, Inserm, CHU Lille, UMR-S 1172, Laboratory Development and Plasticity of the Neuroendocrine Brain, Jean-Pierre Aubert Research Center, 1 Place de Verdun, 59045 Lille, France.
² University of Lille, Inserm, CHU Lille, UMR-S 1172, Laboratory Development and Plasticity of the Neuroendocrine Brain, Jean-Pierre Aubert Research Center, 1 Place de Verdun, 59045 Lille, France. Electronic address: paolo.giacobini@inserm.fr.

PMID: 31577927
DOI: 10.1016/j.cmet.2019.09.005

Abstract

Emerging evidence indicates that the composition of the gut microbiome might affect metabolic homeostasis as well as reproductive fitness in women. In Nature Medicine, a new study by Qi et al. (2019), provides exciting insights into how gut microbiota dysbiosis may drive development of polycystic ovary syndrome (PCOS) and insulin resistance.

Publication types

Comment

MeSH terms

Bile
Female
Fertility
Gastrointestinal Microbiome*
Humans
Interleukin-22
Interleukins
Polycystic Ovary Syndrome*

Substances

Interleukins

Grants and funding

725149/ERC_/European Research Council/International