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J Hum Reprod Sci. 2019 Jul-Sep;12(3):177-181. doi: 10.4103/jhrs.JHRS_83_19.

Perinatal Outcomes Following Assisted Reproductive Technology.

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Division of Women's Health, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Department of Reproductive Medicine, Christian Medical College, Vellore, Tamil Nadu, India.


As the use of routine assisted reproductive technology (ART) becomes widespread along with the extended applications such as ART with donor gametes, surrogacy, and preimplantation genetic testing (PGT), it becomes more pertinent to evaluate risks associated with them. Perinatal outcomes and long-term safety for the women and children are paramount. In this review, we aimed to detail the perinatal outcomes in relation to the ART procedures routinely applied as the extended applications of ART with a focus on singleton pregnancies. While there seems to be a higher risk of adverse perinatal outcomes with some of the ART procedures, the absolute risk increase is generally low. It is important for clinicians to have this knowledge to better counsel and care for their patients.


Assisted reproductive technology; low birth weight; perinatal outcomes; preterm birth

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