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J Chin Med Assoc. 2019 Sep 27. doi: 10.1097/JCMA.0000000000000210. [Epub ahead of print]

Measles re-emerges and recommendation of vaccination.

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Department of Pediatrics, Keelung Hospital, Ministry of Health and Welfare, Taiwan, ROC.
Institute of Emergency and Critical Care Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Section of Nephrology and Immunology, Department of Pediatrics, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.


Measles is a highly infectious viral illnesses and is one of the world most contagious diseases that can affect in all people if they have not been vaccinated or have not had it before. Before measles vaccine become available in 1963, major epidemic occurred approximately every 2-3 years and thus 99% of the people were thought to have been infected naturally with measles virus and immune for life. In 2000, measles was declared eliminated from the United States, and yet 1215 cases have been reported from 30 states as of August 22, 2019. Currently there are several large measles outbreaks universally and some people who were not immune and they need to get their measles, mumps, rubella (MMR) vaccine in order to prevent measles outbreaks. As vaccination coverage increases, the average age of measles infection can change to adolescents and young adults. In addition, the protective antibodies derived from vaccination might decrease gradually, the risk of measles infection in young adults is increasing regardless of international travelling.

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