Five-Year Follow-up of a Severe Case of Pertussis in Oregon, 2012

Public Health Rep. 2019 Nov/Dec;134(6):587-591. doi: 10.1177/0033354919879727. Epub 2019 Sep 30.

Abstract

Oregon continues to face epidemics of pertussis, and infants younger than 2 months of age have the highest incidence and rates of hospitalization and complications. We describe the medical course and sequelae of an infant's severe pertussis illness through age 5½ years. The child has failed to meet developmental milestones, requires substantial medical care, and bears the burdens of chronic lung disease, stroke, epilepsy, impaired neurodevelopment, and problems with vision. The medical and social burden of pertussis among infants too young to be vaccinated underscores the importance of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccination during pregnancy.

Keywords: complications; infants and long-term sequelae; pertussis; severity; vaccination.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Child, Preschool
  • Diphtheria-Tetanus-acellular Pertussis Vaccines / administration & dosage
  • Epidemics*
  • Female
  • Follow-Up Studies
  • Hospitalization
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Mothers
  • Neurodevelopmental Disorders
  • Oregon
  • Pregnancy
  • Vaccination*
  • Whooping Cough / complications*
  • Whooping Cough / epidemiology*
  • Whooping Cough / therapy*

Substances

  • Diphtheria-Tetanus-acellular Pertussis Vaccines