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Hepatology. 2019 Sep 30. doi: 10.1002/hep.30976. [Epub ahead of print]

Reply letter to Almasi-Hashiana A et al.

Author information

1
Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.
2
Department of Tropical Medicine and Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan.
3
Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
4
School of Medicine, National Yang-Ming University, Taipei, Taiwan.
5
Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Abstract

We thank Almasi-Hashiana et al. for their interest in and constructive comments on our study investigating the factors associated with seroreversion of anti-hepatitis A antibodies among HIV-positive patients who had completed 2 doses of hepatitis A vaccination with documented serconversion. In an infectious disease outbreak, the risk of exposure to the infectious agent may evolve with time and location. Thus, these factors were likely to become strong confounders for the outcome of seroreversion in this study. The purpose of the matching in the case-control analysis of our study was to mitigate the confounding effects.

PMID:
31566772
DOI:
10.1002/hep.30976

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