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Pediatr Allergy Immunol. 2019 Sep 28. doi: 10.1111/pai.13130. [Epub ahead of print]

Quality of life associated with maternal anxiety disorder in Russian children and adolescents with food allergy.

Author information

School of Applied Psychology, University College Cork, Cork City, Ireland.
Department of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Veltischev Research and Clinical Institute for Pediatrics of the Pirogov Russian National Research Medical University, Moscow, Russia.
City Clinical Hospital No 31, Moscow, Russia.
Specialist Allergy and Clinical Immunology Department, RNTNE Hospital, University College London Hospitals NHS Foundation Trust, London, UK.
Department of Paediatrics, Imperial College London, London, UK.
The In-VIVO Global Network, an Affiliate of the World Universities Network (WUN), USA.
Solov'ev Research and Clinical Center for Neuropsychiatry, Moscow, Russia.



Food allergy negatively impacts the quality of life (QoL) and has been associated with increased maternal anxiety. There is currently a lack of data assessing QoL of food-allergic children and adolescents in Russia. We aimed to evaluate the performance of the Food Allergy Quality of Life Questionnaire (FAQLQ) measures in a Russian sample of children, adolescents, and mothers and to investigate association between child QoL and maternal general anxiety.


FAQLQ and Food Allergy Independent Measures (FAIM) were translated to Russian to be completed by participants. Mothers also filled the General Anxiety Disorder (GAD-7) questionnaire. Reliability, construct, and discriminant validity of the FAQLQs and association between FAQLQ scores and general anxiety were assessed.


A total of 142 participants completed FAQLQ and FAIM. In total, 126 mothers completed GAD-7 questionnaire. All FAQLQs showed excellent internal consistency (α > 0.94). The means for the FAQLQ-PF, FAQLQ-CF, and FAQLQ-TF varied according to the number of foods avoided, severity of symptoms, and FAIM and GAD scores (ηp2 0.40 P < .001). One in 5 mothers had GAD-7 score indicative of moderate-to-severe anxiety. Association strength between GAD and FAQLQ increased with age. GAD score was associated with FAQLQ-PF score, controlling for multiple confounders.


The FAQLQ showed good reliability and validity in Russian. This study identified number of foods avoided and reported reaction severity being associated with greater QoL impairment in Russian children and adolescents affected by food allergy. The significant association found between general anxiety in parents and QoL in children and adolescents has practice, screening, and resource implications.


children; food allergy; maternal anxiety; quality of life


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