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Georgian Med News. 2019 Jul-Aug;(292-293):54-56.


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Ilia State University, Tbilisi, Georgia.


The present paper aims to summarize and review available research on the manifestations of comorbid depression in persons with ASD (Autism spectrum Disorder) and its impact on the course of autism;as well as to review the pharmacological treatment of comorbid depression with ASD. The existence of a comorbid depression affects the state of individuals with ASD, which often remains unnoticed for the people around. Literary review permits us to get familiar with the peculiarities of clinical manifestations of comorbid depression in autism, risk factors for comorbid depression the importance of diagnosis and the methods of pharmacological intervention. Few issues have been identified: the necessity of raising awareness and drawing attention to the clinical features of comorbid depression especially in low functioning persons. The nessecity of regular screening persons with ASD screening of all persons having ASD for determining the existence of depression and suicidal thoughts. The necessity of adaptation of relevant diagnostic instruments, which will be an important aid tool to diagnose comorbid depression in autism. The necessity of more research to establish guidelines for pharmacological management of symptoms for comorbid depression disorder.

[Indexed for MEDLINE]

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