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Microbiol Resour Announc. 2019 Sep 26;8(39). pii: e00993-19. doi: 10.1128/MRA.00993-19.

Complete Genome Sequence of Herpes Simplex Virus 1 Strain McKrae.

Author information

1
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
2
Sequencing Facility, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
3
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA timamichi@mail.nih.gov.
#
Contributed equally

Abstract

Herpes simplex virus 1 (HSV-1) strain McKrae is highly virulent and relatively neuroinvasive in animal models compared with other wild-type HSV-1 strains. To identify the genetic determinants that lead to the unique phenotypes of the McKrae strain, we sequenced its genome with PacBio single-molecule real-time (SMRT) technology and resolved the complete sequence.

PMID:
31558635
DOI:
10.1128/MRA.00993-19
Free PMC Article

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