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Mayo Clin Proc. 2019 Oct;94(10):2072-2086. doi: 10.1016/j.mayocp.2019.03.029. Epub 2019 Sep 19.

Medication-Assisted Treatment for Opioid-Use Disorder.

Author information

1
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN. Electronic address: Oesterle.tyler@mayo.edu.
2
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN.
3
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN; Mayo Clinic, Jacksonville, FL.
4
Washington University School of Medicine, Department of Psychiatry, and National Council, Washington University in St. Louis, Institute for Public Health, St. Louis, MO.

Abstract

The United States is in the midst of a national opioid epidemic. Physicians are encouraged both to prevent and treat opioid-use disorders (OUDs). Although there are 3 Food and Drug Administration-approved medications to treat OUD (methadone, buprenorphine, and naltrexone) and there is ample evidence of their efficacy, they are not used as often as they should. We provide a brief review of the 3 primary medications used in the treatment of OUD. Using data from available medical literature, we synthesize existing knowledge and provide a framework for how to determine the optimal approach for outpatient management of OUD with medication-assisted treatments.

PMID:
31543255
DOI:
10.1016/j.mayocp.2019.03.029
[Indexed for MEDLINE]

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